[splco_heading size=”15″ align=”left” margin=”30″]The announcement of remdesivir being a possible drug treatment against the deadly virus follows closely on research published in the Journal of Biological Chemistry, with scientists at the University of Alberta showing the drug is highly effective in stopping the replication mechanism of COVID-19.[/splco_heading]
Chair of medical microbiology and immunology at the University of Alberta, Matthias Götte said: “We were optimistic that we would see the same results against the SARS-CoV-2 virus.
“We obtained almost identical results as we reported previously with MERS, so we see that remdesivir is a very potent inhibitor for coronavirus polymerases.
“If you target the polymerase, the virus cannot spread, so it’s a very logical target for treatment.
“These coronavirus polymerases are sloppy and they get fooled, so the inhibitor gets incorporated many times and the virus can no longer replicate.”
Polymerase is any of several enzymes which catalyse the formation of DNA or RNA from precursor substances in the presence of pre-existing DNA or RNA acting as a template.
According to numerous studies, remdesivir is a very potent inhibitor for coronavirus polymerases, demonstrating its potential for combatting COVID-19.
It also shows activity in the lab and in animals against related coronaviruses including SARS and MERS-Co-V.
US has indicated to move over Hydroxychloroquine in the treatment of Covid-19 , US scientist Dr. Anthony Fauci has claimed to have found a much better solution to treat and block the coronavirus, the US experts said that the Hydroxychloroquine has more harms than benefits.
White House health advisor Dr. Anthony Fauci asserted that Remdesivir showed quite good news
According to Dr. Fauji, Remdesivir has set a new standard of care for COVID-19 patients.
More than 1,000 volunteers are a part of this international drug trial.
According to Dr. Fauci, Remdesivir has a “clear-cut significant positive effect in diminishing time to recovery.”
The time to recovery for patients taking the drug is 11 days, compared with 15 days in the placebo group.
“What it has proven is that the drug can block this virus,” he said
Remdesivir is also claimed to have a survival benefit, with a mortality rate of 8% versus 11.6% for the placebo group.
He also said, the mortality benefit of Remdesivir has not yet reached statistical significance.
The drug will be the ‘standard of care’ Dr. Fauci has claimed
Remdesivir is an antiviral medication develoed by the American biopharmaceutical company Gilead Sciences.
A study by Science Daily looked at the effectiveness of remdesivir against a key enzyme of coronavirus which causes COVID-19.
The search for a treatment of the deadly disease is already in human trials.
The study noted: “Scientists have shown that the drug remdesivir is highly effective in stopping the replication mechanism of the coronavirus that causes COVID-19.
[splco_quote]“The finding follows closely on research demonstrating how the drug worked against the Middle East Respiratory Syndrome (MERS) virus, a related coronavirus.”[/splco_quote]